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PLUMED is an open source library for free energy calculations in molecular systems whichworks which works together with some of the most popular molecular dynamics engines. Free energy calculations can beperformed be performed as a function of many order parameters with a particular focus on biological problems, usingstate using state of the art methods such as metadynamics, umbrella sampling and Jarzynski-equation based steered MD. The software, written in C++, can be easily interfaced with both fortran and C/C++ codes.
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