Description
HMMER is used for searching sequence databases for homologs of homologsof protein sequences, and for making protein sequence alignments. It implements Itimplements methods using probabilistic models called profile hidden Markov models Markovmodels (profile HMMs). Compared to BLAST, FASTA, and other sequence alignment sequencealignment and database search tools based on older scoring methodology,HMMER aims to be significantly more accurate and more able to detect remote homologs remotehomologs because of the strength of its underlying mathematical models. In the pastthepast, this strength came at significant computational expense, but in the new HMMER3 newHMMER3 project, HMMER is now essentially as fast as BLAST.
More information
- Homepage: https://hmmer.org/
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